Although my personal experience is a non-scientific study of ONE, consumers of protein shakes and energy bars should be aware that these convenient edibles can increase your risk for kidney disease and/or kidney stone formation (uric stones). There are more than one type of kidney stone. Some result from a build-up of calcium and most pass through our urine without us knowing. But, if they expand to sizes of 2-3mm or more, get ready for some mean back pain, potential fever, possible nausea and hematuria (blood in urine).